Denham is a village and civil parish in the South Buckinghamshire district of Buckinghamshire, England. It is north west of Uxbridge and north of junction 1 of the M40 motorway. The parish has two notable golf courses within its boundaries, The Denham and The Buckinghamshire Golf Clubs.

The village name is derived from the Old English for “homestead in a valley”. It was listed in the Domesday Book of 1086 as Deneham.

The whole of Denham Parish is located within the Colne Valley Regional Park which stretches from Rickmansworth in the north to Staines in the south, Harefield and Uxbridge in the east to Gerrards Cross and Slough in the west.